Platelet Rich Plasma for Insufficient Endometrium
ConditionInfertility of Uterine Origin
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorReproductive Medicine Associates of New Jersey
About this trial
To determine the effectiveness of an intrauterine PRP infusion on endometrial thickness and in vitro fertilization (IVF) outcomes in a population of infertile women with a history of unresponsive thin endometrium.
Eligibility criteria
Qualifiers
Patients who have previously undergone at least 2 unsuccessful frozen embryo transfer cycles, defined as failure to achieve a sustained clinical pregnancy (visualization of intrauterine gestational sac on ultrasound or a cancelled embryo transfer cycle due to inadequate endometrial thickness
Patients with a diagnosis of thin endometrial lining (less than or equal to 6 mm maximum thickness) during prior unsuccessful or canceled embryo transfer cycles.
Disqualifiers
Fewer than 2 prior unsuccessful or canceled frozen embryo transfer cycles.
Most recent unsuccessful embryo transfer prior to January 1, 2017.
Mullerian anomalies, excluding arcuate uterus
Concurrent submucosal fibroids, unrepaired uterine defects or present indication for uterine surgery
Trial design
Treatments tested in this trial
- Platelet Rich Plasma Intrauterine infusion
- Normal saline Intrauterine infusion
Treatment groups
62 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov