Pleural Bleomycin vs Mechanical Abrasion in Malignant Pleural Effusion
ConditionMalignant Pleural Effusion
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorAssiut University
About this trial
Comparision between pleurodesis by pleural abrasion using medical thoracoscopy and bleomycin instillation via indwelling pleural catheter. Evaluating the effectiveness of pleural abrasion using medical thoracoscopy in patients with malignant pleural effusion and evaluating the role of ROSE in diagnosis and management of malignant pleural effusion
Eligibility criteria
Qualifiers
Patients who are 18 years old or more.
patients with rapidly accumulating moderate & massive malignant pleural. effusion that need frequent aspiration to relieve dyspnea and affect quality of life of the patient.
Disqualifiers
patients not fit for thoracoscoy.
patients with life expectency less than 1 month .
trapped lung (endobronchial lesion).
excessive pleural adhesios.
Trial design
Treatments tested in this trial
- Group 1 (mechanical pleurodesis)
- Group 2 chemical pleurodesis by bleomycin)
Treatment groups
70 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov