Pleuroscopy First Versus Thoracentesis First in Patients With Suspected Malignant Pleural Effusions
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorIcahn School of Medicine at Mount Sinai
About this trial
This is a randomized control trial of patients with suspected malignant pleural effusions to compare whether patients who have a thoracentesis or pleuroscopy (pleural biopsy) obtain an adequate biopsy, achieve a diagnosis, and begin cancer-directed therapy faster.
Eligibility criteria
Qualifiers
Referral for diagnostic pleural procedure.
Age ≥ 18 years.
Suspected malignant pleural effusion (Suggestive radiologic appearance (based on computed tomography or positron emission tomography) OR suspected cancer with associated effusion.)
Disqualifiers
Inability to provide informed consent.
Needs emergent drainage.
Pleural effusion is known to be malignant.
Suspected transudative, infectious or inflammatory effusion etiology.
Trial design
Treatments tested in this trial
- Pleuroscopy first
- Thoracentesis first
Treatment groups
98 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov