POCD After Major Gynecologic Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorFatihhan Zeytun
About this trial
This prospective observational cohort study aims to determine the incidence of early postoperative cognitive dysfunction (POCD) in patients undergoing major gynecological surgery. Cognitive function will be assessed using the Montreal Cognitive Assessment (MoCA) preoperatively and on postoperative day 3. POCD will be defined as a ≥20% relative decline or ≥2-point decrease in MoCA score. The study will also evaluate the association between POCD and perioperative clinical, surgical, and inflammatory parameters.
Eligibility criteria
Qualifiers
Female patients aged ≥18 years
Scheduled for elective major gynecological surgery under general anesthesia
Total abdominal hysterectomy and/or bilateral salpingo-oophorectomy
Open or laparoscopic surgical approach
Disqualifiers
Pre-existing dementia or major neurocognitive disorder
History of cerebrovascular event within the previous 3 months
Severe visual or hearing impairment preventing cognitive assessment
Emergency or hemodynamically unstable surgery
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Fatihhan Zeytun
Lead sponsor
Kocaeli City Hospital
Sponsor institution
Source ClinicalTrials.gov