Point-of-Care Ultrasound in Chronic Heart Failure
ConditionCardiovascular Diseases
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
AgeNot listed
SponsorMasaryk University
About this trial
This study aims to determine whether Point-of-Care Ultrasound (POCUS)-guided treatment is non-inferior to standard NT-proBNP-based care in ambulatory patients following hospitalization for heart failure (HF) over a 12-month follow-up period.
Eligibility criteria
Qualifiers
Patients after hospitalization for acute heart failure (AHF)
Symptoms (shortness of breath, oedema, decreased exercise tolerance, increase in abdominal circumference)
Clinical signs (jugular vein distention, hepatojugular reflux, third heart sound, wet lung crackles, pitting oedema) or signs of congestion on CT, X-ray or ultrasound
NT-proBNP >450 pg/mL <55 years old, >900 pg/mL 55-75 years old, >1800 pg/mL >75 years old
Disqualifiers
pregnancy or lactation
under 18 years of age,
current AHF due to a transient cause (Takotsubo syndrome, neurogenic myocardial stunning, septic cardiomyopathy, cardiac tamponade, pulmonary embolism with acute cor pulmonale, thyrotoxicosis, bradycardia <40/min)
planned surgical treatment of the HF cause, CRT implantation or valvular repair ≤ 30 days ago, STEMI or coronary angiography with PCI or CABG ≤ 30 days ago, untreated AV block III. and II. degree type 2, planned or previous heart transplantation, myocarditis ≤ 6 months ago, complex congenital heart disease, cardiac amyloidosis, hypertrophic and restrictive cardiomyopathy, constrictive pericarditis
Trial design
Treatments tested in this trial
- HF focused POCUS
- Standard Care (in control arm)
Treatment groups
112 Participants
are divided into 2 treatment groupsSponsors and collaborators
Masaryk University
Lead sponsor
Brno University Hospital
Collaborator
Source ClinicalTrials.gov