Polyphenol Metabotypes in People With Diabetes Type 2
ConditionType 2 Diabetes Mellitus (T2DM)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-85
SponsorUniversity Hospital, Ghent
About this trial
This cross-sectional study seeks to characterize the overall polyphenol metabotype in patients with T2DM in comparison to age-matched individuals without diabetes. Additionally, the study aims to identify factors that influence the polyphenol metabotype (transit time and gut microbial capacity to degrade polyphenols in particular).
Eligibility criteria
Qualifiers
all participants
between 40-85 years
age-matched individuals without diabetes
BMI between 18.5-30
Disqualifiers
pregnancy of breastfeeding
in last month
acute use of anti/pre/probiotics
start of new drug or dietary supplements
Trial design
Treatments tested in this trial
- Oral Polyphenol Challenge Test / PPPIL
- fasting blood sample
- Fasting urine collection
- 24 hours urine collection
- Questionnaires
- Stool collection
- Transit time determination
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
University Hospital, Ghent
Lead sponsor
University Ghent
Collaborator
University of Parma
Collaborator
Universiteit Antwerpen
Collaborator
Source ClinicalTrials.gov