Position Intervention to Reduce Hypoxemia in Sedation Patients

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorFirst Affiliated Hospital of Zhejiang University

About this trial

Hypoxemia was defined as an SpO2 of \< 90% for any duration. Failure to treat promptly can lead to hypoxemia, which may increase the risks of arrhythmia, nausea and vomiting, and cognitive dysfunction. Studies have shown that body position has a direct impact on respiratory function. In special environments, including outside the operating room where emergency airway management for critically ill and injured patients is needed, or in areas with limited medical resources like remote areas, adopting simple interventions by changing position to maintain patients' respiratory function can be more economical, convenient and safe.

Eligibility criteria

Qualifiers

Patients with 18 years or older

Without obvious cardiovascular or pulmonary dysfunction

Scheduled to undergo procedure or surgery with sedation

Signed the informed consent form

Disqualifiers

Preexisting bradycardia (heart rate <50 beats/min), hypotension (systolic blood pressure < 80mmHg), or hypoxemia (SpO2 < 90%);

Requiring supplemental chronic or intermittent oxygen therapy because of preexisting diseases

Preexisting diseases which unable to tolerate reduced SpO2 or Partial pressure of carbon dioxide in artery (PaCO2) diseases, such as severe cardiovascular and cerebrovascular diseases, intracranial hypertension or severe lung diseases;

Coagulation disorders or a tendency of nose bleeding;

Trial design

Treatments tested in this trial

  • The position adopted when patients undergoing procedure or surgery

Treatment groups

1,752 Participants
are divided into 2 treatment groups

Sponsors and collaborators

First Affiliated Hospital of Zhejiang University

Lead sponsor

Zhejiang Provincial Tongde Hospital

Collaborator

Shenzhen Second People's Hospital

Collaborator

Zhejiang Provincial People's Hospital

Collaborator

The Sixth Affiliated Hospital of Wenzhou Medical University

Collaborator

Lishui Municipal Central Hospital

Collaborator

Ningbo No. 1 Hospital

Collaborator

Zunyi Medical College

Collaborator

The First Affiliated Hospital of Zhengzhou University

Collaborator