Post-Amputation Stump Infection as a Predictor of Persistent Residual Limb Pain: A Prospective Cohort Study

ConditionsResidual Limb Pain Stump Pain Post-Amputation Pain Surgical Site Infection Phantom Limb Pain (PLP)

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18-60

SponsorUkrainian Society of Regional Anesthesia and Pain Therapy

About this trial

Persistent residual limb pain is common after traumatic amputation and significantly impairs rehabilitation and prosthetic use. Postoperative stump infection may contribute to peripheral nerve sensitization, scar fibrosis, and long-term pain persistence. This prospective cohort study aims to determine whether early post-amputation stump infection independently predicts persistent clinically significant residual limb pain at 3 and 6 months after surgery.

Eligibility criteria

Qualifiers

Traumatic upper or lower limb amputation

Enrollment within 4 weeks after surgery

Ability to provide informed consent

Disqualifiers

Pre-existing chronic pain in the affected limb

Severe cognitive impairment

Terminal illness limiting follow-up

Refusal or inability to complete follow-up assessments

Trial design

Treatments tested in this trial

Not listed

Trial groups

150 Participants

are grouped into 1 trial group

Locations

This trial has no locations

Sponsors and collaborators

Ukrainian Society of Regional Anesthesia and Pain Therapy

Lead sponsor

Source ClinicalTrials.gov