About this trial
Musculoskeletal injuries (MSKI) and traumatic brain injury (TBI) are the signature injuries of the ongoing military conflicts. MSKI affect 800,000 Service Members annually and TBI have impacted more than 350,000 in the past 19 years and account for 22% of all combat casualties. Concussion, a mild form of TBI, increases MSKI risk in physically active individuals, including Service Members.
The overall goal of the study is to identify the neuromuscular control mechanisms that increase MSKI risk following concussion. It is hypothesized that concussed individuals will display abnormal neuromuscular function that increases MSKI risk, as compared to non-concussed controls. The study will employ a multi-center, prospective, case-matched control observational study to identify the differences in neuromuscular function following concussion that may contribute to increased MSKI risk. Once the neuromuscular control mechanisms that increase MSKI risk following concussion are identified, targeted risk mitigation strategies can be developed to reduce MSKI risk.
Eligibility criteria
Qualifiers
18-40 years old.
Self-reported asymptomatic post-concussion following enrollment into the study and monitoring of symptoms by research personnel via daily self-reported symptom questionnaires.
Recruited within 5 days following being diagnosed with a concussion, and at least 72 hours prior to self-reporting as asymptomatic.
Access to a functional email address and the internet for completion of patient reported outcomes (PROs) and musculoskeletal injury measures.
Disqualifiers
Post-Concussion Cohort AND Healthy Non-Concussed Cohort
Unable to read or comprehend the English language.
Admitted to the hospital following concussion.
Sustained a concussion not related to physical activity participation (e.g., blast-related injury, fall from a ladder, motor vehicle accident).
Trial design
Treatments tested in this trial
- Post-Concussion Neuromuscular Function and Musculoskeletal Injury Risk Assessment
Treatment groups
Sponsors and collaborators
Walter Reed National Military Medical Center
Lead sponsor
Womack Army Medical Center
Collaborator
University of Georgia
Collaborator