Post Intensive Care Optimization Through Lifestyle Intervention

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMaastricht University Medical Center

About this trial

The quality of the intensive care unit (ICU) has been steadily improving over the years. Although improvements in the acute treatment of critically ill patients have been made, a large number of ICU survivors suffer from severe physical, cognitive and mental health problems persisting months to years after leaving the ICU. Physical impairments occur the most and can be very severe, greatly affecting activities in daily life and subsequently the perceived quality of life of ICU survivors. Although there is an increased awareness of long-term complaints following ICU stay, there is currently a knowledge gap on how to enhance the recovery of ICU survivors 6 to 12 months post-ICU discharge. The overall objective of the current study is to establish the extent of health and functional improvements that can be obtained with an optimized, combined exercise and nutritional intervention in ICU survivors 6 to 12 months post-ICU discharge.

Eligibility criteria

Qualifiers

Aged 18 years and older

Minimum ICU length of stay of 5 days and/or mechanically ventilated for a minimum of 2 days

Persistent physical complaints

Community-dwelling, living independently (non-assisted)

Disqualifiers

Any medical condition that may interfere with the safety of the subjects during exercise or any condition that interferes with assessment of the outcome parameters, in the investigators' judgement in consultation with the responsible physician or treating physician/specialist. In case of a contra-indication for MRI (e.g., a pacemaker), subjects will be excluded from this measurement but not necessarily from the study.

Any medical condition or circumstance where supplementation with the nutritional supplement is potentially contra-indicated.

Known allergy to any of the ingredients present in the nutritional supplement.

Simultaneous use of other nutritional supplements during the study period (i.e., unwillingness to stop for the duration of the study).

Trial design

Treatments tested in this trial

  • Combined exercise and nutritional intervention

Treatment groups

35 Participants
are divided into 1 treatment group

Sponsors and collaborators

Maastricht University Medical Center

Lead sponsor

Danone Global Research & Innovation Center

Collaborator