About this trial
Prediction of postoperative lung function is currently based on anatomical segment counting (ASC), which incorporates pulmonary function test (PFT) results. Standard PFTs such as spirometry can only measure pulmonary capacity as an average over the entire lung and do not take regional function differences into account. Nuclear medicine is recommended where regional functional imaging is required to inform surgical decisions. However, nuclear medicine scans are expensive, time consuming and not available in all institutions. CT-ventilation imaging is a cheaper and more accessible alternative to nuclear medicine for informing lung cancer patient treatment choices.
The primary aim is to quantify the difference between predicted postoperative values of pulmonary function metrics derived from CT ventilation imaging and standard anatomical segment counting method.
Eligibility criteria
Qualifiers
Aged 18 years or older.
ECOG performance status 0-2.
Lung cancer surgical candidates.
Undergo SPECT V/Q scans within 8 weeks of registration.
Disqualifiers
Interstitial lung disease.
Pregnant women.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
Locations
1Map coordinates are unavailable for these locations. Locations are shown below instead.
Sponsors and collaborators
University of Sydney
Lead sponsor
Royal North Shore Hospital
Collaborator