Post Operative RT for Limited Spine Metastases
ConditionSpine Metastases
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age20+
SponsorNational Taiwan University Hospital
About this trial
To evaluate patients with limited spine metastases treated with total spondylectomy followed by conventional radiotherapy or debulking surgery followed by SBRT or conventional RT. The study primary endpoint is one year local control.
Eligibility criteria
Qualifiers
Patients who had pathologically proved solid cancer, with radiographic evident limited spine metastases indicative and feasible for spondylectomy or debulking surgery.
Patients with maximum two continuous level of spine metastases need for surgery are eligible. Patients who have other spine metastases but not necessary for surgery are allowed.
A preoperative gadolinium enhance MRI should be obtained up to 8 weeks before enrollment.
Patients aged at least 20 years old are eligible.
Disqualifiers
Patients received prior radiotherapy to the index spine level.
Patients who cannot receive Gadolinium enhanced MRI due to pacemaker or metal implant or who cannot receive contrast enhanced CT scan due to impaired renal function.
Patients who have hematological cancer or primary spine tumor will be excluded for enrolment.
Patients who cannot tolerate radiotherapy immobilization.
Trial design
Treatments tested in this trial
- Spondylectomy
- SBRT
Treatment groups
111 Participants
are divided into 3 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov