Post Pandemic Pneumococcal Carriage Among Children and Adults
ConditionPneumococcal Carriage
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age7+
SponsorUniversity of Central Florida
About this trial
The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city. These data will allow PI to assess the post-pandemic population structure, investigate the phylogenetic relationship between isolates from children and adults, and compare pneumococcal populations across diverse geographic areas.
Eligibility criteria
Qualifiers
Children, ages 7 to 59 months (less than 5 years)
Adults, ages 50 and older
Ability to provide informed consent (from parents for children participants)
ability to read and speak in English
Disqualifiers
Have been on an antibiotic in the last 2 weeks
Have a respiratory infection that would make an nasopharyngeal collection improbable
Have underlying developmental or chronic conditions impacting immune or respiratory function (e.g., immunocompromised, cystic fibrosis, cerebral palsy, paralysis)
Adults unable to consent, individuals who are not yet adults, and prisoners will be excluded from this study.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
900 Participants
are grouped into 2 trial groupsSponsors and collaborators
University of Central Florida
Lead sponsor
Merck Sharp & Dohme Corporation
Collaborator
Source ClinicalTrials.gov