Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic measures are lacking.
This study wants to learn if these problems are related to certain patterns of breathing that babies had while they were in the NICU.
Enrolled in any Institutional Review Board (IRB) protocol of the Pre-Vent Study that had signed consent, or in any IRB protocol of the Pre-Vent Study that authorized re-contact for future research
Born <29 weeks gestational age
Age at enrollment less than 7 years old
Subject was withdrawn from the Pre-Vent study after signing Pre-Vent consent form, for any reason
Subject had no physiological data recorded as part of Pre-Vent
Lack of regulatory approval from local IRB or Department of Children and Family Services (DCFS) to recontact subjects
Adopted by non-consenting family
Ann & Robert H Lurie Children's Hospital of Chicago
Lead sponsor
University of Virginia
Collaborator
Case Western Reserve University
Collaborator
University of Miami
Collaborator
Northwestern University
Collaborator
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
University of Alabama at Birmingham
Collaborator