Postexposure Prophylaxis With Single Dose Doxycycline for the Prevention of Tick-borne Relapsing Fever

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorMedical Corps, Israel Defense Force

About this trial

The goal of this clinical trial is to compare standard treatment (5 days of doxycycline) vs single dose doxycycline for the prevention of tick-borne relapsing fever in soldiers who found bite marks on their bodies after an activity that includes contact with the ground or staying at a site suspected of being infected with ticks. The main question\[s\] it aims to answer are:

* Testing whether preventive treatment with a single dose of doxylin at a dose of 200 mg is effective in preventing recurrent fever, and if so, at what rate * Checking the profile and rate of side effects in each one of the proposed treatment protocols Participants will be treated with standard treatment (5 days of doxycycline) or single dose doxycycline.

Eligibility criteria

Qualifiers

None

Disqualifiers

Known sensitivity or allergy to doxycycline

Fever in the three weeks preceding the performance of the field series

Suspicion of the Tick borne disease with recurrent fever three weeks before performing the

Incompletion of the field series

Trial design

Treatments tested in this trial

  • administration of single dose of doxycycline

Treatment groups

526 Participants
are divided into 2 treatment groups

Locations

This trial has no locations