Postnatal Exercise to Activate Baby's Brown Fat

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorJoslin Diabetes Center

About this trial

The purpose of this study is to learn how exercise and physical activity during pregnancy and after pregnancy may affect the composition of breastmilk. Certain changes in breast milk after exercise may have an impact on how infants use energy. Understanding this process may improve public health recommendations for exercise during and after pregnancy. This study can help investigators learn more about how maternal exercise patterns may affect body growth and obesity risk in infants who are breastfed. This research may help identify how different factors can influence healthy weight and early development in infants.

Eligibility criteria

Qualifiers

18-45 y of age at the time of enrollment

Pre-gravid or first trimester BMI 18.5 -40 kg/m2

Uncomplicated singleton pregnancy

Intention to exclusively breastfeed for >3 months and, if parity >1, that they successfully breastfed a previous pregnancy

Disqualifiers

Any obstetric contra-indication to exercise at 1 month

Diagnosis of uncontrolled (HbA1c >7%) type 1 or type 2 diabetes, or gestational diabetes managed with insulin

Intrauterine growth restriction

Pre-eclampsia or other pregnancy complications

Trial design

Treatments tested in this trial

  • Active group

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Joslin Diabetes Center

Lead sponsor

University of Oklahoma

Collaborator

National Institutes of Health (NIH)

Collaborator