Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorRegion Stockholm

About this trial

High flow nasal oxygen (HFNO) in the immediate postoperative period has been demonstrated to reduce the risk of postoperative pulmonary complications (PPC) after cardiothoracic surgery. In specific groups of patients such as the obese and after upper abdominal surgery the results are contradictive. However, there is lack of evidence if HFNO in the general high-risk patient after abdominal and non-cardiac thoracic surgery can reduce the prevalence of PPC, hypoxaemia and escalation of therapy. Therefore, the investigators aim to compare the use of HFNO with conventional oxygen therapy (COT) in high-risk patients after abdominal and non-cardiac thoracic surgery regarding postoperative pulmonary complications.

Eligibility criteria

Qualifiers

Age > 65 years

BMI >30

Preoperative SpO2 <95 %

Scheduled for lobectomy or pulmonary segment resection

Disqualifiers

Not suitable for postoperative HFNO, as decided by a study member or the anaesthetist in charge (such as total nasal obstruction, skull fracture, facial injuries)

Pregnancy

Not able to understand the study information or sign an informed consent.

Not able to participate with the treatment postoperatively

Trial design

Treatments tested in this trial

  • High Flow Oxygen
  • Oxygen

Treatment groups

200 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Region Stockholm

Lead sponsor

Karolinska Institutet

Collaborator