About this trial
This prospective observational study evaluates postoperative pain intensity and analgesic consumption in patients undergoing total knee arthroplasty (TKA) under different anesthesia techniques. Patients receive either general anesthesia with peripheral nerve block, spinal anesthesia with peripheral nerve block, spinal anesthesia alone, or general anesthesia with an epidural catheter. Pain scores (NRS), analgesic use, adverse effects, patient satisfaction, and the need for therapeutic interventions are assessed during the first 48 hours after surgery. The study aims to identify differences in postoperative pain control and factors associated with hypotension and other complications.
Eligibility criteria
Qualifiers
Age 18-100 years
Primary total knee arthroplasty (TKA)
ASA physical status I-III
Glasgow Coma Scale (GCS) score of 15
Disqualifiers
Revision or reoperation of TKA
ASA score IV or higher
Refusal to participate or inability to provide informed consent
GCS ≤ 14
Trial design
Treatments tested in this trial
- Not listed