Clinical Evaluation of the Postoperative Pain and Substance P levels Following the use of Bioceramic verses Calcium Hydroxide Intracanal Medicaments in Permanent Mandibular molars with Symptomatic Apical Periodontitis
- Patients aged 18-45 years with no sex predilection
Medically free Patients with no systemic conditions that can affect post operative pain response.
Patients should not be taking any pain medications 24 hours before intervention
Positive patients' acceptance for participating in the study
- Medically compromised patients
Patients who have received antibiotic therapy within the last 2 weeks.
Pregnant or lactating women.
Patients with known allergy to any of the irrigants used.