Postural Sway and Counterpressure Maneuvers for Pediatric Syncope

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age6-18
SponsorSimon Fraser University

About this trial

The investigators are interested in whether discrete counterpressure maneuvers, or muscle movements in the lower body, will boost blood pressure and cardiovascular control in children who faint. We will record cardiovascular responses to maneuvers of exaggerated sway, leg crossing, crouching, and gluteal muscle tensing in children who faint (N=20), as well as their height, weight, muscularity, and pubertal (Tanner) stage. Autonomic cardiovascular control will be measured using a Valsalva manoeuvre (expiration against a closed airway for 20 seconds) and a supine-stand test. The primary outcomes are noninvasive measures of cardiovascular responses to the maneuvers (blood pressure, cerebral blood flow, and stroke volume (volume of blood pumped per heartbeat). Comparisons will be made across levels of sex, diagnosis, Tanner stage, muscularity, height, and degree of autonomic control.

Eligibility criteria

Qualifiers

None

Disqualifiers

Suspected or confirmed cardiac arrhythmia (e.g., Wolff-Parkinson-White, Long QT)

Traumatic head injury

New presentation of a seizure disorder OR epilepsy recurrence

Overdose or intoxication

Trial design

Treatments tested in this trial

  • Counterpressure Maneuvers
  • Baseline Stand

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Simon Fraser University

Lead sponsor

Provincial Health Services Authority British Columbia

Collaborator

University of British Columbia

Collaborator

Natural Sciences and Engineering Research Council, Canada

Collaborator