POTS Adrenergic Ab (CIHR Aims #1&2)
ConditionPostural Tachycardia Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-60
SponsorUniversity of Calgary
About this trial
Objective: In this pilot study, we will test the hypothesis that patients with POTS (age 18-60 years) will have a higher percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS.
Eligibility criteria
Qualifiers
Patients who have been previously diagnosed with POTS
Control subjects (patients not diagnosed with POTS)
Age between 18 - 60 years
Males and Females (Give that >80% of POTS patients are female, we will attempt to enroll a similar percentage of female control subjects)
Disqualifiers
Smokers
Overt cause for postural tachycardia, i.e., acute dehydration
Significant cardiovascular, pulmonary, hepatic, or hematological disease by history or prior testing
Highly trained athletes
Trial design
Treatments tested in this trial
- Phenylephrine
- Isoproterenol
Treatment groups
125 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov