Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery

ConditionsPreoperative Phentolamine Intraoperative Esmolol Hypotensive Anesthesia Functional Endoscopic Sinus Surgery

Trial statusNot yet recruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age21-50

SponsorAin Shams University

About this trial

The aim of this study is to evaluate the efficacy of intra-operative phentolamine vs intraoperative esmolol for hypotensive anesthesia in functional endoscopic sinus surgery.

Eligibility criteria

Qualifiers

Age from 21 to 50 years.

Both sexes.

American Society of Anesthesiologists (ASA) physical status I-II.

Disqualifiers

Patients with a medical condition that contraindicated hypotensive anesthesia, such as peripheral vascular disease, cerebrovascular stroke, carotid artery stenosis, previous myocardial infarction, ischemic heart disease, congestive heart failure, limb ischemia, uncontrolled hypertension and raised intracranial tension

Renal disease, liver dysfunction, pregnancy.

Patients on hypnotic or narcotic analgesic.

History of alcohol or drug abuse.

Trial design

Treatments tested in this trial

Phentolamine
Esmolol

Treatment groups

60 Participants

are divided into 2 treatment groups

Sponsors and collaborators

Ain Shams University

Lead sponsor

Source ClinicalTrials.gov