The goal of this observational study is to learn about the comprehensive changes in severe plaque psoriasis (Psoriasis Vulgaris) in adult participants undergoing standard treatment. The main questions it aims to answer are: How clinical signs of psoriasis, such as redness, scaling, and thickness, change after treatment? How specific skin features, visualized under dermoscopy, change after treatment? How participants' perceptions of psoriasis-related disability and overall quality of life improve after treatment? Participants will undergo standard medical treatment for severe psoriasis. Participants will be evaluated at the beginning of the study and again after treatment using clinical skin examinations, dermoscopic imaging, and validated questionnaires (Psoriasis Disability Index and quality of life parameters).
Patients ≥ 6 years of age
Newly diagnosed patients with plaque psoriasis with affected BSA >10%
Indicated for a new systemic therapy (e.g., oral agent, biologics).
Willing and able to provide informed consent for all procedures .
• Non cooperative patients .
Pregnant or breastfeeding women