Precision Medicine in Cardiovascular Surgery Associated Acute Kidney Injury
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorInsel Gruppe AG, University Hospital Bern
About this trial
The goal of this prospective observational study is to define a risk profile for cardiovascular surgery associated acute kidney injury (AKI), using clinical patient characteristics, operation parameters as well as blood and urine laboratory values.
The main question it aims to answer is:
• Does a combination of the factors mentioned above better predict patient outcome than classical factors used to date in clinical practice?
Participants of this study are adults aged 18 and above who are scheduled for elective heart or main artery surgery, and who have given written informed consent.
Eligibility criteria
Qualifiers
Patients undergoing elective cardiovascular surgery, such as valvular replacement surgery, with or without combined coronary artery bypass graft (CABG), or thoracic or abdominal aortic surgery.
Written informed consent obtained prior to surgery.
Disqualifiers
Patients with a kidney transplant or on renal replacement therapy
Severe liver failure, defined by the presence of encephalopathy, Factor V < 50% and INR >1.5 on preoperative blood sample (within 4 weeks).
Trial design
Treatments tested in this trial
- Not listed
Trial groups
No trial groups listed
Sponsors and collaborators
Insel Gruppe AG, University Hospital Bern
Lead sponsor
CSL Behring
Collaborator
Source ClinicalTrials.gov