Predicting Cancer in Pancreatic Cystic Lesions Through Artificial Intelligence

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCentre Hospitalier Universitaire de Nice

About this trial

This international, multicenter retrospective study aims to develop a deep learning (DL)-based predictive model to identify malignant transformation in pancreatic cystic lesions, improving upon current clinical guidelines. The model will integrate clinical, biochemical, and multimodal imaging data. Several 3D convolutional neural networks will be trained using advanced preprocessing, data augmentation, and hybrid fusion techniques. Model performance will be compared to that of existing international guidelines. The study involves no additional procedures for patients and adheres to strict data anonymization and privacy regulations.

Eligibility criteria

Qualifiers

Patients diagnosed with PCL(s ) who underwent pancreatic surgery in one of the participant centers. Surgical indication must adhere to at least one of current guidelines on PCLs management (6), based on clinical, biochemical, and radiological (MR and/or EUS) features.

Pancreatic surgery B83performed for supposed increased risk of cyst(s) malignant degeneration following current guidelines on PCLs management (6).

Absence of clinical, biochemical, radiological, and anatomopathological evidence of pancreatic cancer at pancreatic surgery.

Non-opposition to the anonymous data processing by the included patients.

Disqualifiers

Patients presenting with evidence of pancreatic cancer at surgery.

PCL(s) diagnosis and treatment performed without one between EUS and pancreatic MR. surgery performed in the absence of the criteria proposed by current guidelines.

Unavailability of both preoperative EUS and pancreatic MR data.

Unavailability of postoperative PCL(s) anatomopathological analysis results.

Trial design

Treatments tested in this trial

  • Pancreatic surgery

Treatment groups

250 Participants
are divided into 1 treatment group

Locations

This trial has no locations