Predicting DBS Outcomes in Dystonia Using Wearable Gait Sensors

ConditionDystonia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorRuijin Hospital

About this trial

This study aims to investigate whether preoperative gait characteristics, measured by wearable sensors, can predict the clinical outcomes of Deep Brain Stimulation (DBS) in patients with dystonia. Participants scheduled for DBS surgery will undergo gait analysis using wearable sensors before the procedure. Clinical assessments, including the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) and the SF-36 Health Survey, will be conducted preoperatively and postoperatively to evaluate surgical efficacy and quality of life. The study seeks to identify gait biomarkers that correlate with optimal DBS response.

Eligibility criteria

Qualifiers

Clinically diagnosed with primary or isolated dystonia.

Scheduled to undergo bilateral Deep Brain Stimulation (DBS) surgery.

Able to walk independently or with assistance (sufficient to perform gait analysis).

Willing to participate and sign informed consent.

Disqualifiers

History of other neurological disorders affecting gait (e.g., stroke, severe neuropathy).

Significant orthopedic issues preventing gait assessment.

Cognitive impairment preventing cooperation with study procedures.

Previous functional neurosurgery.

Trial design

Treatments tested in this trial

  • Wearable Gait Sensor Analysis

Treatment groups

No treatment groups listed

Sponsors and collaborators

Ruijin Hospital

Lead sponsor

Suzhou Sceneray Medical Co. , Ltd

Collaborator

Beijing Pins Medical Co., Ltd

Collaborator

Medtronic

Collaborator