About this trial
This study aims to investigate whether preoperative gait characteristics, measured by wearable sensors, can predict the clinical outcomes of Deep Brain Stimulation (DBS) in patients with dystonia. Participants scheduled for DBS surgery will undergo gait analysis using wearable sensors before the procedure. Clinical assessments, including the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) and the SF-36 Health Survey, will be conducted preoperatively and postoperatively to evaluate surgical efficacy and quality of life. The study seeks to identify gait biomarkers that correlate with optimal DBS response.
Eligibility criteria
Qualifiers
Clinically diagnosed with primary or isolated dystonia.
Scheduled to undergo bilateral Deep Brain Stimulation (DBS) surgery.
Able to walk independently or with assistance (sufficient to perform gait analysis).
Willing to participate and sign informed consent.
Disqualifiers
History of other neurological disorders affecting gait (e.g., stroke, severe neuropathy).
Significant orthopedic issues preventing gait assessment.
Cognitive impairment preventing cooperation with study procedures.
Previous functional neurosurgery.
Trial design
Treatments tested in this trial
- Wearable Gait Sensor Analysis
Treatment groups
Sponsors and collaborators
Ruijin Hospital
Lead sponsor
Suzhou Sceneray Medical Co. , Ltd
Collaborator
Beijing Pins Medical Co., Ltd
Collaborator
Medtronic
Collaborator