About this trial
The purpose of this study is to look at how signals in the brain, body, and behavior relate to anxiety and memory function. This project seeks to develop the CAMERA (Context-Aware Multimodal Ecological Research and Assessment) platform, a state-of-the-art open multimodal hardware/software system for measuring human brain-behavior relationships.
The R61 portion of the project is designed to develop the CAMERA platform, which will use multimodal, passive sensor data to predict anxiety-memory state in patients undergoing inpatient monitoring with intracranial electrodes for clinical epilepsy, as well as to build CAMERA's passive data framework and active data framework.
Eligibility criteria
Qualifiers
Patients must have known or suspected Temporal Lobe Epilepsy.
Native or proficient in speaking English or Spanish.
Stereoelectroencephalography (sEEG) cases: The implant plan must include hippocampal head, body, and tail electrodes either unilaterally or bilaterally.
7th grade reading level (minimum level considered literate for adults)
Disqualifiers
Hearing impaired (i.e., not corrected with a hearing aid)
Unable to read the newspaper at arm's length with corrective lenses.
Objective intellectual impairment (estimated IQ < 70)
Any history of Electroconvulsive Therapy or psychosis (except postictal psychosis for patients)
Trial design
Treatments tested in this trial
- CAMERA (Context-Aware Multimodal Ecological Research and Assessment)
Treatment groups
Sponsors and collaborators
Columbia University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator
Rutgers University
Collaborator
University of Minnesota
Collaborator