Health Trials

Prediction of Propofol Effect-Site Concentration Associated With Deep Anesthesia

ConditionAnesthesia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorCiusss de L'Est de l'Île de Montréal

About this trial

The goal of this observational study is to explore the variability of the concentration at the effect site (Ce) of propofol to reach deep anesthesia (DA) during induction of general anesthesia in adults.

The investigators hypothesized that there is a great variability in this Ce that could be precisely explained by

* Electroencephalographic (EEG) features available prior to induction of anesthesia * Cognitive performance * Patients characteristics Participants will undergo preoperative cognitive testing and awake EEG. Then, induction of general anesthesia will be performed using continuous infusion of propofol. The Ce at which Deep anesthesia is observed will be recorded.

Eligibility criteria

Qualifiers

Scheduled for any kind of surgery under general anesthesia.

Adults

Disqualifiers

Inability to communicate in French or English,

Known allergy or intolerance or other medical condition that precludes the use of prescribed general anesthesia protocol for this study,

Patients requiring rapid sequence induction,

Anticipated or known difficult intubation patient,

Trial design

Treatments tested in this trial

  • Cognitive testing
  • electroencephalogram
  • High density electroencephalogram
  • General anesthesia

Treatment groups

No treatment groups listed

Sponsors and collaborators

Ciusss de L'Est de l'Île de Montréal

Lead sponsor

Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

Collaborator

Source ClinicalTrials.gov