Predictive Algorithms for Critical Rehabilitation Outcomes

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-90
SponsorWuhan University

About this trial

An increasing amount of evidence from evidence-based medicine indicates that early rehabilitation intervention for patients receiving mechanical ventilation is safe and feasible, and can promote functional recovery and reduce hospital stay. However, the conscious state, respiratory function, and daily living activities of these patients after being discharged from the ICU vary greatly, and some patients do not show obvious benefits. How to identify which patients may have benefit from early rehabilitation is a key issue that needs to be addressed in critical care rehabilitation. This study aims to investigate the clinical data related to the disease of the ICU survivors who received mechanical ventilation as the research object, by collecting their clinical data when receiving early rehabilitation intervention, and constructing a clinical prediction model for the efficacy of early rehabilitation intervention in the ICU through the selection of optimal regression equation or machine learning algorithm. The application of this model can effectively determine whether ICU inpatients need early rehabilitation intervention, thereby reducing complication rates and improving their quality of life.

Eligibility criteria

Qualifiers

Age older than 18 years;

Received mechanical ventilation, including endotracheal intubation and tracheostomy, during ICU admission;

Met the rehabilitation intervention indications outlined in the "Chinese Expert Consensus on Neurocritical Rehabilitation" during ICU admission and underwent corresponding early rehabilitation interventions, including but not limited to arousal therapy for consciousness disorders, early active/passive mobilization, comprehensive pulmonary rehabilitation, etc.;

No mortality events occurred during ICU admission;

Disqualifiers

Pediatric patients under 18 years of age;

Hospitalized patients in the ICU who did not receive mechanical ventilation;

Patients in the ICU who did not undergo early rehabilitation interventions;

mortality events occurred during ICU admission;

Trial design

Treatments tested in this trial

  • Early rehabilitation intervention

Treatment groups

250 Participants
are divided into 1 treatment group

Sponsors and collaborators

Wuhan University

Lead sponsor

General Hospital of the Yangtze River Shipping/Wuhan Brain Hospital

Collaborator

Wuhan Wuchang Hospital

Collaborator