Pancreaticoduodenectomy (PD) is a complex procedure performed in patients with malignant or benign tumors of the pancreatic head and periampullary region, associated with high morbidity and mortality. Postoperative pancreatic fistula (POPF) is the most common and clinically significant complication following PD. In this study, the investigators aim to determine the predictive risk factors for clinically related postoperative pancreatic fistula (CR-POPF) in the preoperative, intraoperative and postoperative period in patients that underwent PD. The total number of 100 participants expected to be included in this research who underwent PD between 2025 and 2026.
Patients with resectable distal common bile duct carcinoma, periampullary carcinoma, duodenal carcinoma, and carcinoma of the head of the pancreas.
No evidence of metastasis.
Radiological non-involvement of superior mesenteric vein & portal vein.
American Society of Anesthesiologists (ASA) scores I & II.
Unfit patients for surgery due to severe medical illness.
Inoperable patients with distant metastases, including peritoneal, liver, distant lymph node metastases, and involvement of other organs.
Irresectable tumors in diagnostic laparoscopy.
History of other malignant disease.