Predictors of Emergency Department Use in Frail Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorUniversity of Pisa

About this trial

When admitted to the emergency department (ED), elderly non-autonomous patients show high risk of adverse health outcomes. The prompt identification of ED use risk factors in such population is hence needed. While cognitive impairment is a known clinical risk factor, biomarkers of most prevalent dementias have been scarcely investigated as possible ED use predictors. Within this context, this prospective study aims at exploring whether plasma phospho-tau181 and cerebrovascular burden can predict ED use at 6 months in elderly non-autonomous patients, irrespective of frailty.

Eligibility criteria

Qualifiers

fluency in Italian language,

age higher than 64 years,

loss of autonomies of daily living as assessed by the Katz Activities of Daily Living or in the Lawton Instrumental Activities of Daily Living questionnaires,

having performed routinary blood exams in the 6 months prior to recruitment

Disqualifiers

withdrawal of the informed consent

Trial design

Treatments tested in this trial

  • Plasma phosphorylated Tau 181

Treatment groups

110 Participants
are divided into 1 treatment group

Sponsors and collaborators

University of Pisa

Lead sponsor

Azienda Ospedaliero, Universitaria Pisana

Collaborator