Predictors of Post-Thrombectomy Cognitive Impairment in Acute Ischemic Stroke Patients
ConditionIschemic Stroke, Acute
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAssiut University
About this trial
This prospective cohort study investigates predictors of post-stroke cognitive impairment (PSCI) in patients undergoing endovascular thrombectomy (EVT) for acute ischemic stroke due to large vessel occlusion. Adult patients with successful reperfusion (mTICI 2b-3) will be followed at 3 and 6 months to assess cognition, functional recovery, and depression. Predictors across clinical, procedural, radiological, and laboratory domains will be analyzed. The study aims to identify risk factors for PSCI, estimate its prevalence, and evaluate its impact on outcomes.
Eligibility criteria
Qualifiers
Adults (≥18 years).
Acute ischemic stroke due to anterior circulation LVO confirmed by imaging undergoing EVT per guidelines.
Successful reperfusion (mTICI 2b-3)
Able to provide consent.
Disqualifiers
Severe aphasia/coma interfering with cognitive assessment.
Pre-existing dementia ( using Arabic version of the Short Form of the Informant Questionnaire on Cognitive Decline in the Elderly).
Non-ischemic etiology.
Death within 72 hours.
Trial design
Treatments tested in this trial
- Not listed
Trial groups
120 Participants
are grouped into 1 trial groupLocations
Sponsors and collaborators
Source ClinicalTrials.gov