To assess the feasibility and preliminary effectiveness of a Cardio-Oncology Prehabilitation program in patients at high-risk of developing Cardiovascular (CV) events in improving Cardiorespiratory fitness (CRF) and reducing acute CV complications in Hematopoietic stem cell transplant (HSCT) recipients.
Adult 18 years or older
Referred for HSCT evaluation
Presence of least one CV risk factor at enrollment (hypertension, hyperlipidemia, atrial fibrillation, obesity, heart failure, history of coronary artery disease, diabetes)
Able to ambulate unassisted
Severe anemia (hemoglobin <7 gm/dl)
Untreated high-risk coronary artery disease (left main, triple vessel disease)
Severe aortic stenosis
Recent fracture as assessed via self-report
University of Michigan Rogel Cancer Center
Lead sponsor
National Institutes of Health (NIH)
Collaborator
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator