Preliminary Efficacy Analysis of "C" Single Flap Plasty Reconstruction After Laparoscopic Proximal Gastrectomy

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorDaorong Wang

About this trial

The incidence of proximal gastric cancer has increased significantly in recent years. This may be due to weight gain, alcohol consumption, gastroesophageal reflux disease (GERD), and precancerous lesions. With a deeper understanding of the pattern of lymph node metastasis and the emergence of anti-reflux procedures, proximal gastrectomy has gradually received clinical attention. For early-stage upper gastric cancer and esophagogastric combination cancer cases that are expected to have a good prognosis, the ideal surgical procedure should be to preserve the distal stomach to improve the quality of life and to choose a reasonable digestive tract reconstruction method to prevent reflux. The anti-reflux effect of various proximal gastrectomy digestive tract reconstruction methods and the advantages and disadvantages of various surgical procedures are controversial, and the recognized ideal reconstruction method has not yet been established. Therefore, we propose a reconstruction called the "C" Single Flap Plasty Reconstruction. This study aimed to investigate the efficacy and safety of proximal gastrectomy combined with "C" Single Flap Plasty Reconstruction in the treatment of gastric cancer.

Eligibility criteria

Qualifiers

Age between 18-80 years old, male or female;

Pathological diagnosis of preoperative endoscopic biopsy: the tumor is located in the upper 1/3 of the stomach (including the esophagogastric junction), and the clinical staging of gastric cancer: Ia and Ib (T1N0M0, T1N1M0, and T2N0M0) according to the eighth edition of the AJCC ;

No distant metastasis was observed on preoperative chest radiograph, abdominal ultrasound, or upper abdominal CT;

ASA grade 1-3;

Disqualifiers

Patients diagnosed with primary tumors or distant metastasis;

Patients whose tumor is located in the greater curvature side of the stomach;

Patients with coagulation dysfunction that could not be corrected;

Patients who were diagnosed with viral hepatitis and cirrhosis;

Trial design

Treatments tested in this trial

  • "C" Single Flap Plasty Reconstruction
  • Normal Reconstruction

Treatment groups

50 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Daorong Wang

Lead sponsor

Northern Jiangsu People's Hospital

Sponsor institution