Preliminary Efficacy Trial of a Digital Intervention for Depression and Cannabis Use
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorMassachusetts General Hospital
About this trial
The purpose of this study is to examine the feasibility, acceptability, and preliminary efficacy of a digital intervention for co-occurring cannabis use and depression. Participants will be randomized to complete Amplification of Positivity - Cannabis Use (AMP-C) or symptom tracking. The main outcomes will include changes in depressive symptoms and cannabis use, as well as usability ratings.
Eligibility criteria
Qualifiers
Aged ≥ 18 years
Resides in the United States
Able to read and understand English and willing to provide informed consent/comply with the study protocol
Moderate depressive symptom severity, as indicated by the Patient Health Questionnaire-9 (PHQ-9)
Disqualifiers
History of a psychotic disorder or bipolar disorder type I/II
Active suicidal ideation or intent based on the Columbia-Suicide Severity Rating Scale
Current psychotherapy engagement
Changes in psychotropic medication within six weeks of the start of study
Trial design
Treatments tested in this trial
- Amplification of Positivity - Cannabis Use (AMP-C)
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
Massachusetts General Hospital
Lead sponsor
National Institute on Drug Abuse (NIDA)
Collaborator
Source ClinicalTrials.gov