Prenatal Ultrasonographic Assessment of Fetal Thyroid in Patients With Thyroid Pathology

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18-45
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna

About this trial

The goal of this observational study is to evaluate the possibility to use prenatal ultrasonography for diagnosis and prognostic guidance in cases of suspected fetal thyroid changes in fetuses belonging to women with thyroid disease and women with low obstetric risk (i.e., pregnancy not complicated by maternal and/or fetal pathology) between 14 and 37 gestational weeks.

The main question it aims to answer is:

Is it possible to diagnose thyroid disease in fetuses early using measurable parameters of the fetal thyroid through ultrasonography?

Eligibility criteria

Qualifiers

Participants between 14 and 37 gestational weeks, who will be followed for the entire period of pregnancy, up to delivery, at the same enrolling center

Obtaining informed consent for participation in the study

Maternal age between 18 and 45 years (extremes included)

Participants with good understanding of the Italian language

Disqualifiers

Smoking participants

Patients with BMI>30

Absence of correct dating of pregnancy within the first trimester

Pathological conditions (e.g., malabsorptive or socioeconomic conditions that may interfere with fetal growth)

Trial design

Treatments tested in this trial

  • Description of the trend of major thyroid ultrasound biometric parameters

Treatment groups

440 Participants
are divided into 3 treatment groups