Preoperative Biliary Drainage in Malignant Biliary Obstruction
ConditionPancreatic Cancer
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Pecs
About this trial
The first alarming symptom of a malignancy of the pancreas or periampullary tumor can be obstructive jaundice (OJ). Pancreato-duodenectomy (PD) combined with oncological treatment can provide long disease-free survival in resectable cases. The literature regarding the preoperative biliary drainage is controversial. The aim of this multicenter, prospective observational cohort study is to investigate the role of preoperative drainage, and to compare it with surgery alone.
Eligibility criteria
Qualifiers
Patients ≥ 18 years
OJ of malignant origin (pancreatic head or periampullary tumor)
Total bilirubin level ≥ 40 μmol per liter
Signed written informed consent
Disqualifiers
Proved metastasis
Irresectable tumor
Neo-adjuvant chemotherapy
Co-existing malignancy
Trial design
Treatments tested in this trial
- Preoperative drainage and pancreatoduodenectomy
- Pancreatoduodenectomy
Treatment groups
353 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov