Preoperative Risk Stratification in Endometrial Cancer for Tailoring Lymph Node Staging

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorUniversity Hospital Hradec Kralove

About this trial

The goal of this observational study is to evaluaty the accuracy of current risk stratification of patients with endometrial cancer and to redefine lymph node staging recommendations based on real-world clinical data. The main question it aims to answer is:

Is there any group of patients who doesn't need lymph node staging for proper indication of adjuvant treatment? Participants are note taking any intervention. They are treated according to current standard of care and followed 3-years after primary surgery.

Eligibility criteria

Qualifiers

Women ≥18 years with newly diagnosed endometrial cancer (any histology)

Undergoing primary surgical management

Preoperative expert ultrasound, CT scan (could be waived in low risk cases)

Preoperatively early-stage (stage I-II) of EC

Disqualifiers

Neoadjuvant treatment

Recurrent or metastatic disease at diagnosis

Inadequate imaging or tissue samples

Cancer synchronous duplicity

Trial design

Treatments tested in this trial

  • No Intervention: Observational Cohort

Treatment groups

No treatment groups listed