Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma (FUSION-01)

ConditionsSoft Tissue Sarcoma Retroperitoneal Sarcoma Radiotherapy Side Effect Ultra-hypofractionated Radiotherapy Stereotactic Ablative Radiotherapy

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18+

SponsorCancer Institute and Hospital, Chinese Academy of Medical Sciences

About this trial

To investigate the feasibility and peri-operative complications of preoperative hypo-fractionated radiotherapy followed by surgery for retroperitoneal sarcoma

Eligibility criteria

Qualifiers

Primary soft tissue sarcoma of retroperitoneal or infra-peritoneal spaces of pelvis

Sarcoma not originated from bone structure, abdominal or gynecological viscera

All disease can be included safely within one radiotherapy field

Absence of extension through the sciatic notch or across the diaphragm

Disqualifiers

metastatic disease

Tumor was previously treated by radiotherapy

Involvement of liver, pancreatic head or duodenum

Trial design

Treatments tested in this trial

ultra-hypofractionated radiotherapy

Treatment groups

50 Participants

are divided into 1 treatment group

Sponsors and collaborators

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Lead sponsor

Source ClinicalTrials.gov