About this trial
To compare the safety and efficacy of preoperative versus postoperative revascularization strategies in patients with coronary heart disease undergoing time-sensitive non-cardiac surgery.
Eligibility criteria
Qualifiers
Age ≥18 years
Diagnosis of coronary heart disease with non-emergent indication for PCI confirmed by coronary angiography:
Non-ST-elevation acute coronary syndrome (NSTE-ACS) at low or intermediate ischemic risk
Moderate or severe stenosis of the left main coronary artery
Disqualifiers
Age >80 years
Severe thrombocytopenia (platelet count <50×10⁹/L)
Cardiogenic shock, severe heart failure (NYHA class IV, Killip class IV, or LVEF ≤35%), malignant arrhythmias (including cardiac arrest, asystole, ventricular fibrillation, or sustained ventricular tachycardia), or other life-threatening conditions requiring resuscitation
Moderate-to-severe valvular heart disease, high-grade atrioventricular block, or other severe cardiac/pulmonary dysfunction incompatible with the planned surgery
Trial design
Treatments tested in this trial
- Non-cardiac surgery followed by postoperative PCI
- Preoperative PCI followed by delayed non-cardiac surgery ~3 months later