Aims and Objectives
1. Choose which adjunctive therapies, at what dose, and for how long 2. Choose the dose(s) of IV furosemide to be used as the comparator 3. Choose primary and secondary outcomes 4. Estimate recruitment and engage sites for a future trial
Work package 2a methods overview
1. An online survey of clinicians (doctors, nurses and pharmacists) assessing potential ability to recruit and the acceptability of each adjunct and willingness to support a trial. 2. Evidence generated (survey and reviews) will be considered by an expert panel (N=20-25) including expert clinicians and allied health professionals who care for people with HF using a modified Delphi approach. The panel will make recommendations on all aspects of the trial design. 3. A patient and carer panel of people with a recent hospitalisation (\<6 months) for HF will provide recommendations on trial endpoints. The patient-and-carer advisory group (PCAG) will also input into these discussions.
Recent hospitalisation with heart failure (<6 months) or carer for a person with a recent hospitalisation with heart failure.
Able to participate in online group discussions in English
None
Hull University Teaching Hospitals NHS Trust
Lead sponsor
Hull York Medical School
Collaborator
University of Birmingham
Collaborator
Robertson Centre for Biostatistics University of Glasgow Glasgow G12 8QQ
Collaborator