About this trial
Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky. When they lose their oxygen, they form into the shape of a sickle or crescent. This can cause pain and tissue damage. Significant decrease in exercise capacity was seen in sickle cell anemic children. In the absence of a guidelines that can guide the prescription of exercise in SCD children. This study is a step for determine the forms of prescription of pain on the balance and muscle strength to build up in future studies a safety of physical exercises for children with sickle cell anemia and improve their functional abilities.
Eligibility criteria
Qualifiers
Age range range was 9-14 years old.
Could follow given instructions.
Children with Sickle cell anemia were medically stable, and take their medications regularly.
Children with Sickle cell anemia had experience of chronic pain that lasts more than 6 months.
Disqualifiers
Defined cardiovascular or respiratory disorders.
Renal failure.
Myocardial infarction, mainly within last month.
Unstable angina.
Trial design
Treatments tested in this trial
- Pressure pain tolerance measurement using Digital Pressure Algometer
- Balance assessment using HUMAC balance system
- Lower limb muscular strength using Lafayette hand held dynamometer
Treatment groups
Sponsors and collaborators
Adly A Adam
Lead sponsor
Cairo University
Sponsor institution