Pressure Recording Analytical Method Parameters and Their Relationship With Hypotension in Hypertensive Patients

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorRecep Tayyip Erdogan University

About this trial

Perioperative anesthesiologists can benefit from easily obtainable hemodynamic variables detecting or quantifying the lack of an adequate compensatory capacity of the cardiovascular system in order to optimize patient management and improve patient outcomes. Parameters of the Pressure Recording Analytical Method (PRAM; Vygon, Padua, Italy) of the MostCare system, specifically cardiac cycle efficiency has been proposed as such variables. Yet, their value in anesthesia and especially in hypertensive patients is not studied. The goal of the PRAM-in-HYPO study is to prospectively evaluate the relationship between cardiac reserve and efficiency and cardiovascular risk factors in patients wo will undergo major surgical procedures using the state-of-the-art hemodynamic monitors. Also the investigators aim to build a predictive model to identify patients with decreased cardiac reserve due to hypertension and other cardiovascular risk factors, who are susceptible to post-induction hypotension. The investigators seek to include high-risk patients or patients presenting for major surgery, who are monitored with an advanced hemodynamic monitor to adequately evaluate the differences in cardiac reserve and cardiac efficiency.

Eligibility criteria

Qualifiers

Age at least 18 years

Undergoing major surgery under general anesthesia

Expected surgery time >2 h

Expected length of postoperative stay >2 d

Disqualifiers

Refuse to consent to the study

Arterial wave form distortion

Cardiac arrhythmia

Inappropriate identification of the dicrotic notch for any reason

Trial design

Treatments tested in this trial

  • Passive leg raising

Treatment groups

660 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Recep Tayyip Erdogan University

Lead sponsor

Turkish Society of Thoracic and Cardio-Vascular Anesthesia and Intensive Care

Collaborator