About this trial
This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS. Clinical data (MRI, lab results, medical history, labs, and sleep studies) of MS patients will be collected and analyzed. This will be done to study correlations between MRI, clinical data, lab studies and sleep studies. There is specific interest in the type of sleep apnea associated with MS, and whether MRI or clinical metrics of MS severity correlate with presence or absence of sleep apnea.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Written consent
Over age 18
Confirmed diagnosis of multiple sclerosis
Disqualifiers
cannot provide informed consent
Trial population
Subjects with a confirmed diagnosis of multiple sclerosis will be the inclusion criteria for this study. As patients come to clinic for their routine clinical care visits, the investigators will identify presence of MS. The investigators will identify approximately 400 people will take part in this study at Beth Israel Deaconess Medical Center. Approximately 200 people each will take part in this study at UMass Medical Center MS Center and at Lahey MS Center. A total of 800 people will take part in this study at all study sites.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Home Sleep Study Data
Home Sleep Study Data
Secondary outcomes
Questionnaire data
sleep quality, quality of life, depression and anxiety scales
Sponsors and contacts
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