Prevalence and Impact of Obstructive Sleep Apnea in Multiple Sclerosis

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorBeth Israel Deaconess Medical Center

About this trial

This study will evaluate the influence of sleep apnea on clinical and radiological features of MS. Sleep apnea is associated with hypoxemia during sleep, which is likely detrimental to MS. Clinical data (MRI, lab results, medical history, labs, and sleep studies) of MS patients will be collected and analyzed. This will be done to study correlations between MRI, clinical data, lab studies and sleep studies. There is specific interest in the type of sleep apnea associated with MS, and whether MRI or clinical metrics of MS severity correlate with presence or absence of sleep apnea.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Written consent

Over age 18

Confirmed diagnosis of multiple sclerosis

Disqualifiers

cannot provide informed consent

Trial population

Subjects with a confirmed diagnosis of multiple sclerosis will be the inclusion criteria for this study. As patients come to clinic for their routine clinical care visits, the investigators will identify presence of MS. The investigators will identify approximately 400 people will take part in this study at Beth Israel Deaconess Medical Center. Approximately 200 people each will take part in this study at UMass Medical Center MS Center and at Lahey MS Center. A total of 800 people will take part in this study at all study sites.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

800 Participants
are grouped into 2 trial groups
Group A: Patients with Multiple Sclerosis with obstructive sleep apnea
Group B: Patients with MS without obstructive sleep apnea

Trial outcomes

Primary outcomes

1

Home Sleep Study Data

Home Sleep Study Data

Time frame
1 year

Secondary outcomes

1

Questionnaire data

sleep quality, quality of life, depression and anxiety scales

Time frame
1 year

Other outcomes

Sponsors and contacts

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