Prevalence and Natural History of Functional Gastrointestinal Disorders Among At-risk Infants.

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age3-24
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS

About this trial

The goal of this observational study is to learn about the prevalence and characteristics of functional gastrointestinal disorders (FGID) in at risk infants (former preterm infants and those with birth asphyxia) during the first 2 years of life. The main questions it aims to answer are:

* evaluate the prevalence of symptoms related to gastro-esophageal reflux (GER), of functional gastrointestinal disorders during the first 2 years of life * describe growth parameters during follow-up up to the corrected age of 2 years Participants will be assessed clinically and with a structured questionnaire based on the Rome IV criteria to describe FGID.

Eligibility criteria

Qualifiers

infants with gestational age at birth < 31 weeks

infants with gestational age at birth < 37 weeks and major respiratory or neurologic morbidity

infants with history of perinatal asphyxia

Disqualifiers

lack of informed consent

diagnosis of congenital or other major gastrointestinal disease (i.e. inflammatory bowel disease, cancer)

Trial design

Treatments tested in this trial

  • Questionnaire, clinical examination

Treatment groups

No treatment groups listed