Prevalence of Tapia's Syndrome in Weaning Unit
ConditionTapia's Syndrome
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHopital Forcilles
About this trial
Tapia syndrome is a rare and poorly understood pathology. It is defined by a concomitant attack of the recurrent (branch of X) and hypoglossal (XII) nerves of peripheral or central origin. It is characterized by the paralysis of a vocal cord and the ipsilateral half of tongue. This damage is most often unilateral but it can also be bilateral. It results in dysphonia and swallowing disorders.
Tapia syndrome is a rare and poorly understood pathology. To date, less than 100 cases have been described in the literature. Previous works are mainly case reports and literature reviews. No prevalence study has been performed to date. Furthermore, disagreements persist regarding the semiology. Indeed, the involvement of the soft palate is not always described.
Eligibility criteria
Qualifiers
Hospitalized in weaning unit
Duration of orotracheal intubation in the ICU greater than 48 hours;
Glasgow score greater than or equal to 13 ;
Patient at least 18 years of age at the time of inclusion;
Disqualifiers
Known history of ENT or neurological pathologies (stroke, head trauma, neurodegenerative disease, brain tumor, ENT cancer);
Known tumors in the vicinity of the X-nerve pathway;
Ortner's syndrome (left recurrent nerve compression through the left atrium in mitral stenosis);
Left lung cancer with subaortic lesion;
Trial design
Treatments tested in this trial
- Diagnosis of Tapia's Syndrome
Treatment groups
247 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov