Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorUniversity of Pecs
About this trial
Recurrence of acute pancreatitis (AP) is often facilitated by regular alcohol consumption and smoking. An applied lifestyle intervention focusing on the cessation of alcohol consumption and smoking might prevent the recurrence of AP. REAPPEAR Study is a randomized controlled trial and a cohort study focusing on the efficacy of the lifestyle intervention and the effect of quitting alcohol and smoking respectively.
Eligibility criteria
Qualifiers
Patient hospitalized with alcohol-induced AP (defined by the revised Atlanta criteria 38)
Every day smoker (defined as an adult patient who smoked at least 100 cigarettes in his or her lifetime, and now smokes on a daily basis; as per the CDC definition), with at least 1-year history of smoking
Aged 18-80 years
Provided written informed consent
Disqualifiers
Possible etiologies for AP other than alcohol (eg. gallstone-related, hypertriglyceridemia above 11.5 mM 40-42, hypercalcemia, viral infection) if the etiological cannot be terminated during the index admission (lack of same admission cholecystectomy, familiar hypertrygliceridemia) and cases with combined etiological factors will be excluded
Untreated, decompensated or severe mMajor psychiatric illnesses (e.g. schizophrenia, bipolar disorder, dementia)
Currently taking part in a smoking cessation program
Undergoing active or palliative treatment for malignancy
Trial design
Treatments tested in this trial
- Standard intervention only
- Standard intervention plus repeated intervention
Treatment groups
364 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov