About this trial
This is a study of the use of an antibacterial solution, Hypochlorous acid, to prevent infection in vascular surgery bypass grafts. The solution will be used at the end of operations to insert a prosthetic vascular surgery bypass graft, to wash the wound and the vascular bypass graft before the wound is closed. The patients in this study will be undergoing surgery for problems with narrowed and or blocked arteries. The presence or absence of a graft infection will be followed for 12 months following the surgery. Prosthetic vascular graft infections have significant implications for patients with high rates of death and amputation, hence preventing them will have significant benefits for patients and the health care system.
Eligibility criteria
Qualifiers
Patients undergoing elective or emergent open insertion of prosthetic vascular grafts to the abdominal and/or lower limb vessels, including all prosthetic bypass grafts and patch grafts
Patients 18 years of age or older
Able to provide informed consent in English
Disqualifiers
Patients undergoing vascular surgery that does not involve the insertion of a prosthetic graft to the abdominal and/or lower limb vessels by an open operation
Patients under the age of 18 years
Patients who are unable to provide informed consent in English
Trial design
Treatments tested in this trial
- Hypochlorous acid
Treatment groups
Sponsors and collaborators
Hamilton Health Sciences Corporation
Lead sponsor
McMaster University
Collaborator