Preventive Effect of Limited Decompression on Adjacent Segment Following Posterior Lumbar Interbody Fusion
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorPeking University Third Hospital
About this trial
This is a prospective single-center study. Patients requiring posterior lumbar interbody fusion (PLIF) for degenerative disease are prospectively enrolled and followed. Patients enrolled in this study have asymptomatic pre-existing spinal canal stenosis at adjacent segment. This study will focus on the effects of preventative limited decompression at adjacent segment.
Eligibility criteria
Qualifiers
A clear diagnosis of lumbar spinal stenosis, and surgical level of L4-S1 (The levels to be operated on were decided by matching the clinical symptomatology with the radiological findings of the spinal levels that needed decompression);
Patients have asymptomatic pre-existing spinal canal stenosis (cerebrospinal fluid occlusion grade=1) at adjacent segment.
Failed at least eight weeks conservative treatment;
Disqualifiers
Unstable factors (slip, rotation, lateral bending, etc.) in adjacent segment L3/4;
Preoperative sagittal and coronal imbalance of the spine;
Lumbar infection and/or tumor diseases;
A previous history of lumbar fusion surgery.
Trial design
Treatments tested in this trial
- Limited decompressions at adjacent segment with asymptomatic pre-existing spinal canal stenosis
- Responsible segments fused
Treatment groups
200 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov