Stage II seminoma is a type of cancer that is usually highly curable and most often affects young men.
Radiotherapy is an effective treatment, but it can sometimes cause side effects in the long term and, rarely, increase the risk of developing another cancer later in life.For this reason, more targeted treatments are being explored, such as proton therapy (PBT). This type of radiotherapy uses protons to better focus the treatment on the tumor while reducing exposure to the surrounding healthy tissues.The goal is to treat the cancer effectively while minimizing side effects as much as possible.
Age ≥ 18 years
Male gender
ECOG Performance status 0 - 1
Histologically confirmed diagnosis of testicular seminoma
Non-seminomatous germ cell tumor histology
Incomplete definitive surgical orchiectomy, including diagnostic biopsy alone
Prior or concurrent second malignancy other than non-melanoma skin cancer, unless disease free for a minimum of five years
Prior radiotherapy to the abdominal or pelvic region
Istituto Clinico Humanitas
Lead sponsor
AIRC (Italian Association for Cancer Research)
Collaborator